Sodium/potassium ratio alter was with the hypertension alter: odds of people approach for salt/potassium proportion losing fitness checkup

Sodium/potassium ratio alter was with the hypertension alter: odds of people approach for salt/potassium proportion losing fitness checkup

Recently, the sodium (Na)/potassium (K) ratio was reported to be associated with blood pressure (BP). A Na/K ratio self-monitoring device using spot urine was established recently. Here, we assessed whether the urinary Na/K ratio change measured using the Na/K device was associated with BP change in a health checkup setting. We targeted 12,890 participants who attended the health checkup in Tome City, Miyagi between 2017 and 2018. Tome City introduced urinary Na/K ratio measurements during health checkups since 2017. For each year, we compared the baseline characteristics according to the urinary Na/K ratio and BP level. We assessed the relationship between change in urinary Na/K ratio and BP change using multiple regression analyses adjusted for age, sex, and change in body mass index (BMI) and alcohol intake. The average urinary Na/K ratio was significantly lower in 2018 than in 2017 (5.4 ± ۳.۰ to 4.9 ± ۲.۲, P < 0.01). The systolic BP of the participants in 2018 (130.9 ± ۱۷.۴ mmHg) was lower than that in 2017 (132.1 ± ۱۷.۹ mmHg). Moreover, the change in systolic BP and diastolic BP was positively associated with the change in urinary Na/K ratio. In conclusion, the association of the change in urinary Na/K ratio with hypertension and changes in systolic and diastolic BP can be explained by a change in alcohol intake, BMI, and urinary Na/K ratio. Therefore, measuring the urinary Na/K ratio in community settings is a potential population approach for counteracting hypertension.


Recently, it actually was reported that the newest sodium (Na)/potassium (K) proportion are regarding the blood pressure levels (BP) when you look at the a mix-sectional studies [step 1,2,step 3,4]. This really is questioned given that high Na and you can K intake was known getting linked to large and you may lowest BP, correspondingly [5,six,7]. Simultaneously, research has been presented on the site viewpoints and affairs adding to this new Na/K proportion in earlier times year [8, 9].

Sodium/potassium proportion alter is actually on the blood pressure changes: chances of inhabitants method for sodium/potassium proportion reduction in fitness checkup

When you look at the a residential area mode, it is difficult for us to evaluate the genuine Na consumption just like the Na consumption try usually reviewed from the 24-h urine range. Even in the event numerous equations to have quoting Na consumption or K intake using everyday destination urine was recently depending, this type of equations aren’t real adequate to render viewpoints to your people [10,eleven,12]. Also, given that picture need measuring Na, K, and you will creatinine profile inside the a research, it entails several weeks to find the outcomes for individuals. Even though participants realize that salt protection is made for decreasing BP, he’s got no way out of examining its Na level.

Recently, an excellent Na/K ratio notice-monitoring product playing with room urine is actually built . Although it didn’t measure the genuine Na consumption level, it will bring viewpoints about your urinary Na/K equilibrium within a few minutes. More over, a keen interventional otherwise observational studies with this particular display ideal that the will be a useful tool so you can imagine the fresh new urinary Na/K proportion [thirteen, 14].

Hence, although we haven’t any means to fix assess the Na/K ratio into the wellness checkup setup, i considered that assessing this new urinary Na/K proportion during the a healthcare checkup webpages have the potential to add viewpoints for the standard population about their Na/K proportion and could impact impact change, improvement in step, Na/K ratio reduction, and you may BP prevention. Within this investigation, i reviewed if the urinary Na/K ratio changes counted toward Na/K proportion dimension equipment are regarding dominicancupid the BP change independent out of confounding points including bmi (BMI) transform and alter in the alcoholic drinks consumption and you will compared this new BP height and urinary Na/K proportion at the people peak.

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